An efficient prebiotic synthesis of cytosine and uracil

Authors: M. P. Robertson, S. L. Miller IN contrast to the purines, the routes that have been proposed for the prebiotic synthesis of pyrimidines from simple precursors give only low yields. Cytosine can be synthesized from cyano-acetylene and cyanate; the former precursor is produced from a spark discharge in a CH4/N2 mixture and is an abundant interstellar molecule. But this…

Cyanoacetylene in Prebiotic Synthesis

Authors: R. A. Sanchez, J. P. Ferris, L. E. Orgel Cyanoacetylene is a major nitrogen-containing product of the action of an electric discharge on a mixture of methane and nitrogen. It reacts with simple inorganic substances in aqueous solution to give products including aspartic acid, asparagine, and cytosine. 10.1126/science.154.3750.784