Radiolysis of Nucleosides in Aqueous Solutions: Base Liberation by the Base Attack Mechanism

Authors: S. Fujita On the radiolysis of uridine and some other nucleosides in aqueous solution, a pH-dependent liberation of uracil or the corresponding base was found. e and HO-2 gave no freed bases, although many oxidizing radicals, including OH, Cl2, Br2, (CNS)2 and SO4, did cause the release of unaltered bases, depending on the pH of the solutions. The base…